Ensembl ID ENSG00000006125 Gene ID 163 Accession 563
Gene Symbol AP2B1 Alias ADTB2;AP105B;CLAPB1;AP2-BETA Full Name adaptor related protein complex 2 subunit beta 1
Position 17 : 35578046 - 35726413 Length 148368 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary The protein encoded by this gene is one of two large chain components of the assembly protein complex 2, which serves to link clathrin to receptors in coated vesicles. The encoded protein is found on the cytoplasmic face of coated vesicles in the plasma membrane. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

ENSG00000006125 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000006125 AP2B1 -0.5 2.03e-35 KIRC
ENSG00000006125 AP2B1 0.46 7.76e-11 BRCA
ENSG00000006125 AP2B1 1.06 2.74e-12 CHOL
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000006125 AP2B1 tumor 25908786
ENSG00000006125 AP2B1 tumor 28724549
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000006125 AP2B1 SARC 0.00036 high
ENSG00000006125 AP2B1 UVM 0.0025 high
ENSG00000006125 AP2B1 PAAD 0.034 high
ENSG00000006125 AP2B1 THCA 0.036 low
ENSG00000006125 AP2B1 ACC 0.0011 high
ENSG00000006125 AP2B1 LUSC 0.0051 high
ENSG00000006125 AP2B1 HNSC 0.02 high
ENSG00000006125 AP2B1 READ 0.00024 low
ENSG00000006125 AP2B1 BRCA 0.013 high
ENSG00000006125 AP2B1 UCS 0.021 high
ENSG00000006125 AP2B1 OV 0.043 high
ENSG00000006125 AP2B1 BLCA 0.019 high
ENSG00000006125 AP2B1 GBM 0.019 low
ENSG00000006125 AP2B1 SKCM 0.021 low
ENSG00000006125 AP2B1 CESC 0.0082 high
ENSG00000006125 AP2B1 LIHC 0.0014 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000006125 AP2B1 ACC Del 1.947196 0.144353 0.592221 0.277778
ENSG00000006125 AP2B1 SARC Del 2.961664 0.178616 0.461937 0.291829
ENSG00000006125 AP2B1 PCPG Del 4.593430 0.125641 0.634794 0.228395
ENSG00000006125 AP2B1 BRCA Del 5.664298 0.095935 0.430762 0.327778
ENSG00000006125 AP2B1 STAD Amp 1.101423 0.144154 0.425195 0.226757
ENSG00000006125 AP2B1 UCEC Del 3.273849 0.074922 0.587342 0.198516
ENSG00000006125 AP2B1 OV Del 1.633295 0.195588 0.639598 0.834197