Ensembl ID ENSG00000005022 Gene ID 292 Accession 10991
Gene Symbol SLC25A5 Alias T2;T3;2F1;AAC2;ANT2 Full Name solute carrier family 25 member 5
Position X : 119468444 - 119471396 Length 2953 bases Strand Plus strand
Status Confidence Main interacting RNAsN.A.RBP type Non-canonical_RBPs
Summary This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.[provided by RefSeq, Jun 2013]

ENSG00000005022 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000005022 -1.1 7.64e-22 KIRC
ENSG00000005022 0.60 7.22e-23 BRCA
ENSG00000005022 1.45 2.03e-20 KICH
ENSG00000005022 0.90 7.78e-17 LUSC
ENSG00000005022 1.01 6.03e-16 UCEC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000005022 cancer 18267033
ENSG00000005022 cancers 19455236
ENSG00000005022 breast cancer 22198296
ENSG00000005022 gastric cancer 30793479
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000005022 SARC 0.0015 high
ENSG00000005022 STAD 0.05 low
ENSG00000005022 UVM 0.033 high
ENSG00000005022 PAAD 0.048 low
ENSG00000005022 UCEC 0.032 low
ENSG00000005022 LGG 0.036 low
ENSG00000005022 LUSC 0.03 low
ENSG00000005022 HNSC 0.0071 high
ENSG00000005022 KIRP 0.035 low
ENSG00000005022 KICH 0.031 high
ENSG00000005022 PCPG 0.0053 high
ENSG00000005022 THYM 0.036 low
ENSG00000005022 BRCA 0.0015 high
ENSG00000005022 COAD 0.0052 low
ENSG00000005022 UCS 0.014 high
ENSG00000005022 DLBC 0.012 low
ENSG00000005022 KIRC 0.0077 low
ENSG00000005022 PRAD 0.027 high
ENSG00000005022 SKCM 0.0074 high
ENSG00000005022 CESC 0.0023 low
ENSG00000005022 LIHC 0.0088 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency