Ensembl ID ENSG00000004700 Gene ID 5965 Accession 9948
Gene Symbol RECQL Alias RECON;RecQ1;RECQL1 Full Name RecQ like helicase
Position 12 : 21468910 - 21501669 Length 32760 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. The encoded protein is involved in the processing of Holliday junctions, the suppression of sister chromatid exchanges, telomere maintenance, and is required for genotoxic stress resistance. Defects in this gene have been associated with several types of cancer. [provided by RefSeq, Jan 2017]

ENSG00000004700 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000004700 RECQL 0.52 7.05e-11 KIRC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000004700 RECQL colorectal cancers 11888892
ENSG00000004700 RECQL pancreatic cancer 16520463
ENSG00000004700 RECQL cancer 18006573
ENSG00000004700 RECQL cancer 18074021
ENSG00000004700 RECQL pancreatic cancer 18719387
ENSG00000004700 RECQL cancer 19768149
ENSG00000004700 RECQL cancer 20948612
ENSG00000004700 RECQL cancer 21059676
ENSG00000004700 RECQL Cancer 21220316
ENSG00000004700 RECQL cancers 21571861
ENSG00000004700 RECQL tumor 21752281
ENSG00000004700 RECQL cancer 23396353
ENSG00000004700 RECQL cancer 23601052
ENSG00000004700 RECQL cancer 23650516
ENSG00000004700 RECQL ovarian cancer 23951333
ENSG00000004700 RECQL cancers 24213927
ENSG00000004700 RECQL cancers 24287950
ENSG00000004700 RECQL cancer 24623817
ENSG00000004700 RECQL cancer 24688722
ENSG00000004700 RECQL cancer 24854846
ENSG00000004700 RECQL breast cancer 25394896
ENSG00000004700 RECQL epithelial ovarian cancer 25424877
ENSG00000004700 RECQL cancer 25483193
ENSG00000004700 RECQL cancer 25538733
ENSG00000004700 RECQL cancers 25620975
ENSG00000004700 RECQL cancer 25677447
ENSG00000004700 RECQL cancer 25729389
ENSG00000004700 RECQL breast cancer 25915596
ENSG00000004700 RECQL Breast Cancer 25945795
ENSG00000004700 RECQL breast cancer 26125302
ENSG00000004700 RECQL cancer 26358404
ENSG00000004700 RECQL cancer 26455304
ENSG00000004700 RECQL Pancreatic Cancer 26725729
ENSG00000004700 RECQL cancer 26877874
ENSG00000004700 RECQL cancer 27102625
ENSG00000004700 RECQL breast cancer 27125668
ENSG00000004700 RECQL breast cancer 27248010
ENSG00000004700 RECQL non-small cell lung cancer 27565844
ENSG00000004700 RECQL breast cancer 27832498
ENSG00000004700 RECQL Breast Cancers 27837030
ENSG00000004700 RECQL cancer 28186131
ENSG00000004700 RECQL breast cancer 28382090
ENSG00000004700 RECQL cancer 28594346
ENSG00000004700 RECQL Tumour 28878163
ENSG00000004700 RECQL cancer 29080750
ENSG00000004700 RECQL breast cancer 29100281
ENSG00000004700 RECQL breast cancer 29341116
ENSG00000004700 RECQL breast cancer 29351780
ENSG00000004700 RECQL breast cancer 29678143
ENSG00000004700 RECQL hereditary breast and ovarian cancer 29879995
ENSG00000004700 RECQL breast cancer 29914420
ENSG00000004700 RECQL breast cancer 30584360
ENSG00000004700 RECQL breast cancer 30610487
ENSG00000004700 RECQL tumor 30871259
ENSG00000004700 RECQL hereditary breast cancer 31173646
ENSG00000004700 RECQL breast cancer 31312277
ENSG00000004700 RECQL breast cancer 31426369
ENSG00000004700 RECQL triple-negative breast cancer 31444271
ENSG00000004700 RECQL ovarian cancer 31572446
ENSG00000004700 RECQL pediatric cancer 31604778
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000004700 RECQL MESO 0.0012 high
ENSG00000004700 RECQL SARC 0.017 high
ENSG00000004700 RECQL PAAD 0.0052 high
ENSG00000004700 RECQL UCEC 0.0048 low
ENSG00000004700 RECQL ACC 0.0021 high
ENSG00000004700 RECQL KICH 0.0079 high
ENSG00000004700 RECQL LUAD 0.009 high
ENSG00000004700 RECQL BRCA 0.013 high
ENSG00000004700 RECQL UCS 0.016 high
ENSG00000004700 RECQL DLBC 0.046 low
ENSG00000004700 RECQL KIRC 0.00083 low
ENSG00000004700 RECQL PRAD 0.019 high
ENSG00000004700 RECQL BLCA 0.0011 high
ENSG00000004700 RECQL LAML 0.011 high
ENSG00000004700 RECQL SKCM 0.00013 low
ENSG00000004700 RECQL CESC 0.03 high
ENSG00000004700 RECQL LIHC 0.012 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000004700 RECQL LUAD Amp 3.450565 0.177410 0.568270 0.302326
ENSG00000004700 RECQL LGG Amp 2.533871 0.070557 0.774968 0.091618
ENSG00000004700 RECQL PAAD Amp 0.633560 0.078265 0.564629 0.195652
ENSG00000004700 RECQL PAAD Del 0.606406 0.043541 0.402004 0.125000
ENSG00000004700 RECQL TGCT Amp 21.239729 0.687245 1.781885 0.980000
ENSG00000004700 RECQL STAD Amp 0.688077 0.129923 0.623672 0.244898
ENSG00000004700 RECQL OV Amp 0.815445 0.331844 0.965751 0.518135