Ensembl ID ENSG00000004700 Gene ID 5965 Accession 9948
Gene Symbol RECQL Alias RECON;RecQ1;RECQL1 Full Name RecQ like helicase
Position 12 : 21468910 - 21501669 Length 32760 bases Strand Minus strand
Status Confidence Main interacting RNAsN.A.RBP type Canonical_RBPs
Summary The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. The encoded protein is involved in the processing of Holliday junctions, the suppression of sister chromatid exchanges, telomere maintenance, and is required for genotoxic stress resistance. Defects in this gene have been associated with several types of cancer. [provided by RefSeq, Jan 2017]

ENSG00000004700 Expression In 33 Tumors

Ensembl ID Gene symbol Log2 Foldchange Pvaue Cancer
ENSG00000004700 0.52 7.05e-11 KIRC
Ensembl ID Gene symbol Cancer types Pubmed ID
ENSG00000004700 colorectal cancers 11888892
ENSG00000004700 pancreatic cancer 16520463
ENSG00000004700 cancer 18006573
ENSG00000004700 cancer 18074021
ENSG00000004700 pancreatic cancer 18719387
ENSG00000004700 cancer 19768149
ENSG00000004700 cancer 20948612
ENSG00000004700 cancer 21059676
ENSG00000004700 Cancer 21220316
ENSG00000004700 cancers 21571861
ENSG00000004700 tumor 21752281
ENSG00000004700 cancer 23396353
ENSG00000004700 cancer 23601052
ENSG00000004700 cancer 23650516
ENSG00000004700 ovarian cancer 23951333
ENSG00000004700 cancers 24213927
ENSG00000004700 cancers 24287950
ENSG00000004700 cancer 24623817
ENSG00000004700 cancer 24688722
ENSG00000004700 cancer 24854846
ENSG00000004700 breast cancer 25394896
ENSG00000004700 epithelial ovarian cancer 25424877
ENSG00000004700 cancer 25483193
ENSG00000004700 cancer 25538733
ENSG00000004700 cancers 25620975
ENSG00000004700 cancer 25677447
ENSG00000004700 cancer 25729389
ENSG00000004700 breast cancer 25915596
ENSG00000004700 Breast Cancer 25945795
ENSG00000004700 breast cancer 26125302
ENSG00000004700 cancer 26358404
ENSG00000004700 cancer 26455304
ENSG00000004700 Pancreatic Cancer 26725729
ENSG00000004700 cancer 26877874
ENSG00000004700 cancer 27102625
ENSG00000004700 breast cancer 27125668
ENSG00000004700 breast cancer 27248010
ENSG00000004700 non-small cell lung cancer 27565844
ENSG00000004700 breast cancer 27832498
ENSG00000004700 Breast Cancers 27837030
ENSG00000004700 cancer 28186131
ENSG00000004700 breast cancer 28382090
ENSG00000004700 cancer 28594346
ENSG00000004700 Tumour 28878163
ENSG00000004700 cancer 29080750
ENSG00000004700 breast cancer 29100281
ENSG00000004700 breast cancer 29341116
ENSG00000004700 breast cancer 29351780
ENSG00000004700 breast cancer 29678143
ENSG00000004700 hereditary breast and ovarian cancer 29879995
ENSG00000004700 breast cancer 29914420
ENSG00000004700 breast cancer 30584360
ENSG00000004700 breast cancer 30610487
ENSG00000004700 tumor 30871259
ENSG00000004700 hereditary breast cancer 31173646
ENSG00000004700 breast cancer 31312277
ENSG00000004700 breast cancer 31426369
ENSG00000004700 triple-negative breast cancer 31444271
ENSG00000004700 ovarian cancer 31572446
ENSG00000004700 pediatric cancer 31604778
Ensembl ID Gene symbol Disease/phenotype Mutation type Mutated / Total samples Literature
Ensembl ID Gene symbol Cancer P-value Which worse show
ENSG00000004700 MESO 0.0012 high
ENSG00000004700 SARC 0.017 high
ENSG00000004700 PAAD 0.0052 high
ENSG00000004700 UCEC 0.0048 low
ENSG00000004700 ACC 0.0021 high
ENSG00000004700 KICH 0.0079 high
ENSG00000004700 LUAD 0.009 high
ENSG00000004700 BRCA 0.013 high
ENSG00000004700 UCS 0.016 high
ENSG00000004700 DLBC 0.046 low
ENSG00000004700 KIRC 0.00083 low
ENSG00000004700 PRAD 0.019 high
ENSG00000004700 BLCA 0.0011 high
ENSG00000004700 LAML 0.011 high
ENSG00000004700 SKCM 0.00013 low
ENSG00000004700 CESC 0.03 high
ENSG00000004700 LIHC 0.012 high
Ensembl ID Gene symbol Cancer CNV type -log10(q-value) G-score average amplitude frequency
ENSG00000004700 LUAD Amp 3.450565 0.177410 0.568270 0.302326
ENSG00000004700 LGG Amp 2.533871 0.070557 0.774968 0.091618
ENSG00000004700 PAAD Amp 0.633560 0.078265 0.564629 0.195652
ENSG00000004700 PAAD Del 0.606406 0.043541 0.402004 0.125000
ENSG00000004700 TGCT Amp 21.239729 0.687245 1.781885 0.980000
ENSG00000004700 STAD Amp 0.688077 0.129923 0.623672 0.244898
ENSG00000004700 OV Amp 0.815445 0.331844 0.965751 0.518135