Release Notes 08.15.2023 - v2.1 ---------------------------------------------------------------------------------------------------- EuRBPDB was renamed as RBPWorld ---------------------------------------------------------------------------------------------------- 08.15.2023 - v2.1 ---------------------------------------------------------------------------------------------------- - Added literature links in the table, allowing users to conveniently download the associated literature directly. - Repaired issues in the genetic disease page, ensuring accurate and reliable information. - Replaced the term "virus complex results" with "Gene set over-representation analysis of RBPs interacting with SARS-CoV-2 RNA virus" for improved clarity. Additionally, the gene set enrichment results have been reorganized for better usability. - Added links to external resources such as CORUM, REACTOME, and KEGG, enabling users to access relevant information more easily. - Resolved bugs that previously caused the page to crash when requesting large lists of drugs, providing a smoother user experience. - Included the drug name in the table and created links to respective databases, facilitating quick access to additional drug-related information. - Updated the Help document to reflect the latest changes and provide comprehensive guidance to users. - Addressed several minor issues reported by our users, further enhancing the overall stability and usability of EuRBPDB. ---------------------------------------------------------------------------------------------------- EuRBPDB v2 is online! ---------------------------------------------------------------------------------------------------- 06.29.2023 - v2 ---------------------------------------------------------------------------------------------------- - Added genetic disease, RNA virus diseases, and drugs sections to the diseases module, providing valuable information in these areas. - Introduced the Functions module and RNA Interactomes module, unveiling 336 RNA-binding metabolic enzymes, 343 DNA-binding transcription factors, and 100 E3 ubiquitin ligases as RNA targets of various RBPs. - Integrated a Blast tool in the Tools module, enabling users to perform sequence similarity searches conveniently. - Updated the Help document to provide detailed instructions on utilizing the new features and modules. ---------------------------------------------------------------------------------------------------- 09.05.2019 - v1.2 ---------------------------------------------------------------------------------------------------- -Added a "Gene tree" link to the Basic Information of each RBP -Made available all data used for drawing summative bar/pie charts for downloading. -Provided the full name of each cancer type in Cancer interface and the "Cancer Related Information" subpage of each RBP. -Provided orthologs of each non-canonical RBP identified by RBPome in "Ortholog identified by RBPome" section in "Basic Information" subpage of each RBP. -addressed some minor issues found by users. ---------------------------------------------------------------------------------------------------- 08.24.2019 - v1.1 ---------------------------------------------------------------------------------------------------- - Redesigned the RBPredictor. - Added three RBPome datasets: Jurkat_PerezPerri2018NC_RIC, Jurkat_PerezPerri2018NC_eRIC, Hela_Castello2016_RIC, identified 12 additional human non-canonical RBPs. - Added RBP PPI network mutation data. - Added information of mutations occuring within RBDs. - Added literatures on RNA-binding capacity of each RBP. - Refined the display of Gene Models. - Added visual presentation of the RBDs beneath the RBD tables. - All orthologue group of RBPs are available for downloaded in bulk downloaded section. - Made the Search function case insensitive . - Showed all cancer associated RBPs with more than 3 literatures supported in Cancer interface. - Updated the Help document. - Optimized the code of website and speeded up the response time. - Provided the the number of total RBPs, non-canonical RBPs, total number of RNA binding domains (RBDs) in the "Species" page. - Incorporated 4 eCLIP datasets generated from human adrenal gland tissues. ---------------------------------------------------------------------------------------------------- 06.28.2019 - v1.0 ---------------------------------------------------------------------------------------------------- EuRBPDB v1.0 is online!